SCHEMBL26328617

SCHEMBL26328617

CCc1cc(OCCC[Si](C)(OC)OC)cc(C(C)(C)C)c1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.40
CA1 P00915 2/20 0.40
HSPA5 P11021 2/20 0.38
HIF1A Q16665 3/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
PTGS1 P23219 2/20 0.34
CYP2D6 P10635 2/20 0.33
HSD17B10 Q99714 1/20 0.33
PTGS2 P35354 1/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
TYR P14679 1/20 0.33
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26328613 0.81 HSPA5 (0.49) CA2CA1HSPA5HIF1ACYP2C9
SCHEMBL26328608 0.79 GAA (0.42) HSPA5KMT2AMEN1GSK3BGAA
SCHEMBL2879172 0.76 CA2 (0.56) CA2CA1HIF1ACYP2C9CYP2C19
SCHEMBL26328609 0.73 GAA (0.38) HSPA5PTGS1KMT2AMEN1VCAM1
SCHEMBL8959195 0.72 CA2 (0.61) CA2CA1HSPA5HIF1ACYP2C9
SCHEMBL26328619 0.71 HSPA5 (0.43) CA2CA1HSPA5HIF1ACYP2C9
SCHEMBL10990333 0.71 CA2 (0.55) CA2CA1HIF1ACYP2C9CYP2C19
SCHEMBL2883418 0.71 GAA (0.48) CA2CA1HIF1ACYP2C9CYP2C19
SCHEMBL8959243 0.70 CA2 (0.59) CA2CA1HSPA5HIF1ACYP2C9
SCHEMBL8959175 0.70 CA2 (0.63) CA2CA1HSPA5HIF1ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230360821-A1 SILANE FUNCTIONAL STABILIZERS FOR EXTENDING LONG-TERM ELECTRICAL POWER CABLE PERFORMANCE AMINDON INC. 2023-11-09 US disclosed
US-11749422-B2 Silane functional stabilizers for extending long-term electrical power cable performance NOVINIUM, LLC (US) 2023-09-05 US disclosed