SCHEMBL26328619

SCHEMBL26328619

C=CCOc1cc(CC)c(O)c(C(C)(C)C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.43
CA2 P00918 3/20 0.41
CA1 P00915 2/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
HIF1A Q16665 3/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
MAPT P10636 5/20 0.39
ALDH1A1 P00352 4/20 0.39
CYP2D6 P10635 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
USP2 O75604 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
BLM P54132 1/20 0.39
ATM Q13315 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9639084 0.88 CA2 (0.53) CA2CA1SMN1; SMN2HIF1ACYP2C9
SCHEMBL10390640 0.78 CA2 (0.40) CA2CA1SMN1; SMN2HIF1ACYP2C9
SCHEMBL30331506 0.74 ALDH1A1 (0.50) CA2CA1SMN1; SMN2CYP2C9MAPT
SCHEMBL9638077 0.74 ALDH1A1 (0.50) CA2CA1SMN1; SMN2CYP2C9MAPT
SCHEMBL26328615 0.74 HSPA5 (0.58) HSPA5CA2CA1SMN1; SMN2HIF1A
SCHEMBL7523719 0.73 VCAM1 (0.38) SMN1; SMN2MAPTMEN1KMT2APOLB
SCHEMBL10613533 0.73 HSPA5 (0.61) HSPA5CA2CA1SMN1; SMN2HIF1A
SCHEMBL4219860 0.73 CA2 (0.61) HSPA5CA2CA1SMN1; SMN2HIF1A
SCHEMBL17060938 0.73 HSPA5 (0.45) HSPA5CA2CA1SMN1; SMN2HIF1A
SCHEMBL2705478 0.72 HSPA5 (0.63) HSPA5CA2CA1SMN1; SMN2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230360821-A1 SILANE FUNCTIONAL STABILIZERS FOR EXTENDING LONG-TERM ELECTRICAL POWER CABLE PERFORMANCE AMINDON INC. 2023-11-09 US disclosed
US-11749422-B2 Silane functional stabilizers for extending long-term electrical power cable performance NOVINIUM, LLC (US) 2023-09-05 US disclosed