⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26749069 | 0.90 | HSD17B10 (0.30) | — | |
| SCHEMBL4482423 | 0.82 | — | — | |
| SCHEMBL19565595 | 0.78 | — | — | |
| SCHEMBL25806657 | 0.78 | — | — | |
| SCHEMBL7964565 | 0.78 | — | — | |
| SCHEMBL26749028 | 0.77 | CES2 (0.38) | — | |
| SCHEMBL26749029 | 0.77 | CES2 (0.38) | — | |
| SCHEMBL12955457 | 0.76 | — | — | |
| SCHEMBL14789965 | 0.76 | — | — | |
| SCHEMBL19565518 | 0.74 | APLNR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357180-A1 | DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2023-11-09 | — | — | US | disclosed |
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | C4 THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | US | disclosed |