Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21851278 | 1.00 | CYP3A4 (0.47) | CYP3A4CYP1A2CYP2C9CYP2C19TRPA1 | |
| SCHEMBL104529 | 0.82 | CYP3A4 (0.48) | CYP3A4CYP1A2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL1678437 | 0.81 | CYP2D6 (0.65) | CYP3A4CYP1A2CYP2C9CYP2C19LOXL2 | |
| Ammonia Solution, Strong SCHEMBL29040632 | 0.80 | CYP3A4 (0.47) | CYP3A4CYP1A2CYP2C9CYP2C19LOXL2 | |
| Iodide SCHEMBL1750931 | 0.80 | CYP2C9 (0.47) | CYP3A4CYP1A2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL19522791 | 0.79 | CYP3A4 (0.47) | CYP3A4CYP1A2CYP2C9CYP2C19TRPA1 | |
| SCHEMBL8513064 | 0.78 | CYP3A4 (0.55) | CYP3A4CYP1A2CYP2C9CYP2C19TRPA1 | |
| SCHEMBL16321985 | 0.78 | TAAR1 (0.60) | LOXL2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL11062127 | 0.78 | CYP3A4 (0.45) | CYP3A4CYP1A2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL4662841 | 0.78 | CYP3A4 (0.45) | CYP3A4CYP1A2CYP2C9CYP2C19LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | UNIVERSITY OF DELAWARE (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | TST, CYP4F8, CYP4Z1 | CYP3A4 29/4885CYP1A2 129/4885CYP2C9 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.