Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12169540 | 0.83 | ALOX5AP (0.40) | ALOX5APVRK1HTR1D | |
| SCHEMBL7940202 | 0.83 | AGBL2 (0.43) | VRK1PDE2AAGBL2HDAC3HDAC1 | |
| SCHEMBL20089646 | 0.77 | VRK1 (0.32) | ALOX5APVRK1PDE2A | |
| SCHEMBL26340897 | 0.76 | VRK1 (0.37) | VRK1AGBL2 | |
| SCHEMBL34471009 | 0.71 | ALOX5AP (0.41) | ALOX5APPDE2AHTR1D | |
| SCHEMBL111804 | 0.70 | — | — | |
| SCHEMBL31153218 | 0.70 | — | — | |
| SCHEMBL254115 | 0.69 | — | — | |
| SCHEMBL29475255 | 0.69 | — | — | |
| SCHEMBL19996792 | 0.69 | PDE2A (0.33) | PIK3CAPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158626-A1 | ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE THEREOF | MERCK SHARP & DOHME LLC (US) | 2023-08-24 | — | — | WO | disclosed |