Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 11/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999579 | 0.85 | TSHR (0.45) | MTORBRD4NTSR1GAK | |
| SCHEMBL26329960 | 0.81 | ALDH1A1 (0.47) | NTSR1 | |
| SCHEMBL26329876 | 0.80 | LRRK2 (0.39) | NTSR1GAK | |
| SCHEMBL26318011 | 0.80 | DOT1L (0.40) | MTORBRD4NTSR1GAKDPP4 | |
| SCHEMBL26329889 | 0.77 | GAK (0.38) | GAK | |
| SCHEMBL24004017 | 0.71 | TSHR (0.60) | GAK | |
| SCHEMBL23133586 | 0.71 | PRMT5 (0.42) | MTOR | |
| SCHEMBL26317976 | 0.70 | TSHR (0.50) | NTSR1GAK | |
| SCHEMBL26317683 | 0.69 | PDE10A (0.53) | GAK | |
| SCHEMBL25490846 | 0.69 | IP6K1 (0.37) | MTORGAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | MTOR 3/4885BRD4 3048/4885NTSR1 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.