Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 2/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24009992 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTMEN1POLB | |
| SCHEMBL26329876 | 0.81 | LRRK2 (0.39) | MAPTMEN1KMT2ANTSR1NPSR1 | |
| SCHEMBL26329904 | 0.81 | MTOR (0.39) | NTSR1 | |
| SCHEMBL26329889 | 0.81 | GAK (0.38) | ALDH1A1KDM4EMAPTMEN1POLB | |
| SCHEMBL25824152 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTMEN1POLB | |
| SCHEMBL25466142 | 0.79 | KDM4E (0.43) | ALDH1A1KDM4EMAPTMEN1POLB | |
| SCHEMBL25466123 | 0.78 | IP6K1 (0.46) | ALDH1A1KDM4EMAPTMEN1POLB | |
| SCHEMBL24006371 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTMEN1POLB | |
| SCHEMBL26317683 | 0.75 | PDE10A (0.53) | KDM4EMEN1KMT2A | |
| SCHEMBL25491134 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | ALDH1A1 4544/4885KDM4E 3961/4885MAPT 3962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.