Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.69 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.69 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.69 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.69 |
| ▸ | DRD2 | P14416 | 3/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.69 |
| ▸ | HTR2A | P28223 | 3/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.69 |
| ▸ | HRH1 | P35367 | 3/20 | 0.69 |
| ▸ | DRD3 | P35462 | 3/20 | 0.69 |
| ▸ | HTR2B | P41595 | 3/20 | 0.69 |
| ▸ | HTR6 | P50406 | 3/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26330934 | 0.87 | OPRM1 (0.61) | OPRM1OPRK1OPRL1OPRD1CYP1A2 | |
| SCHEMBL9225104 | 0.84 | OPRM1 (0.61) | OPRM1OPRK1OPRL1OPRD1CYP1A2 | |
| SCHEMBL26330800 | 0.84 | CACNA1B (0.52) | OPRM1OPRK1OPRL1OPRD1CYP1A2 | |
| SCHEMBL15494151 | 0.83 | OPRM1 (0.60) | OPRM1OPRK1OPRL1OPRD1CYP1A2 | |
| SCHEMBL26330793 | 0.82 | OPRK1 (0.63) | OPRM1OPRK1OPRL1OPRD1CYP1A2 | |
| Fluspirilene SCHEMBL42082 | 0.82 | OPRM1 (1.00) | OPRM1OPRK1OPRL1OPRD1CYP1A2 | |
| Fluspirilene SCHEMBL15117504 | 0.82 | OPRM1 (1.00) | OPRM1OPRK1OPRL1OPRD1CYP1A2 | |
| SCHEMBL26330944 | 0.82 | OPRM1 (0.61) | OPRM1OPRK1OPRL1OPRD1CYP1A2 | |
| SCHEMBL9998386 | 0.78 | OPRM1 (0.60) | OPRM1OPRK1OPRL1OPRD1CYP1A2 | |
| Fluspirilene SCHEMBL28221293 | 0.78 | OPRM1 (0.91) | OPRM1OPRK1OPRL1OPRD1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286982-A1 | PROTEASOME ENHANCERS AND USES THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2023-09-14 | — | — | US | disclosed |
| US-20230286982-A1 | PROTEASOME ENHANCERS AND USES THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286982-A1 | PROTEASOME ENHANCERS AND USES THEREOF | PSME3, PSME1, PSME4 | OPRM1 4198/4885OPRK1 3611/4885OPRL1 1914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.