SCHEMBL26332277

SCHEMBL26332277

CO[C@](C#N)(CO[PH](=O)N[C@@H](C)C(=O)OCC1CCC1)[C@@H](OC(C)=O)[C@@H](OC(C)=O)c1ccc2c(N)ncnn12

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RIPK1 Q13546 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23819033 0.97 — —
SCHEMBL23819015 0.94 — —
SCHEMBL26332563 0.92 RIPK1 (0.31) RIPK1
SCHEMBL26332408 0.91 RIPK1 (0.30) RIPK1
SCHEMBL26332594 0.90 — —
SCHEMBL23819263 0.89 — —
SCHEMBL23819292 0.84 — —
SCHEMBL23819026 0.83 BTN3A1 (0.34) RIPK1
SCHEMBL26332254 0.83 BTN3A1 (0.34) RIPK1
SCHEMBL23819025 0.83 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767337-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2023-09-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11767337-B2 Antiviral compounds MAVS, HAVCR2, ZC3HAV1 RIPK1 666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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