SCHEMBL26332371

SCHEMBL26332371

CC(=O)O[C@H]1[C@H](c2ccc3c(N)ncnn23)O[C@](C#N)(CO[PH](=O)N[C@@H](C)C(=O)OCC2CCN(CC(F)(F)F)CC2)[C@H]1OC(C)=O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 1/20 0.32
▸ AXL P30530 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26332328 0.90 — —
SCHEMBL23818503 0.86 POLRMT (0.33) —
SCHEMBL23819219 0.86 — —
SCHEMBL23819266 0.85 POLRMT (0.31) —
SCHEMBL30595435 0.85 POLRMT (0.31) —
SCHEMBL23818510 0.85 POLRMT (0.31) —
SCHEMBL23819264 0.85 POLRMT (0.31) —
SCHEMBL26333296 0.84 — —
SCHEMBL23819141 0.80 PIK3CD (0.31) PIK3CD
SCHEMBL26333872 0.80 POLRMT (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767337-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2023-09-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11767337-B2 Antiviral compounds MAVS, HAVCR2, ZC3HAV1 PIK3CD 4286/4885AXL 2783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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