SCHEMBL177366

SCHEMBL177366

O=c1oc2ccccc2cc1-c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 1.00
KDM4E B2RXH2 5/20 1.00
MAOB P27338 4/20 1.00
ALDH1A1 P00352 4/20 1.00
NPC1 O15118 7/20 0.75
SMN1; SMN2 Q16637 4/20 0.75
GAPDH P04406 2/20 0.75
GAA P10253 2/20 0.75
HPGD P15428 2/20 0.75
NCOA1 Q15788 1/20 0.75
NCOA3 Q9Y6Q9 1/20 0.75
ESR1 P03372 1/20 0.75
ESR2 Q92731 1/20 0.75
L3MBTL1 Q9Y468 1/20 0.75
MAPT P10636 3/20 0.71
KMT2A Q03164 2/20 0.68
MIF P14174 1/20 0.68
ADORA3 P0DMS8 2/20 0.60
ADORA2A P29274 2/20 0.60
ADORA1 P30542 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30356319 1.00 RAB9A (1.00) RAB9AKDM4EMAOBALDH1A1NPC1
SCHEMBL250083 0.89 RAB9A (0.79) RAB9AKDM4EMAOBALDH1A1NPC1
SCHEMBL29517170 0.88 RAB9A (0.78) RAB9AKDM4EMAOBALDH1A1NPC1
SCHEMBL7124667 0.86 KDM4E (0.75) RAB9AKDM4EMAOBALDH1A1NPC1
SCHEMBL2929526 0.86 ALDH1A1 (0.75) RAB9AKDM4EMAOBALDH1A1NPC1
SCHEMBL23212283 0.86 RAB9A (0.75) RAB9AKDM4EMAOBALDH1A1NPC1
SCHEMBL30096432 0.86 NCOA1 (1.00) RAB9AKDM4EMAOBALDH1A1NPC1
SCHEMBL14389070 0.86 MAOB (0.75) RAB9AKDM4EMAOBALDH1A1NPC1
SCHEMBL4064740 0.86 ALDH1A1 (1.00) RAB9AKDM4EMAOBALDH1A1NPC1
SCHEMBL8934489 0.86 KDM4E (0.75) RAB9AKDM4EMAOBALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137591-A1 COMPOSITIONS AND DEVICES FOR CONTAINING MEDICAL FLUIDS ICU MEDICAL INC (US) 2026-05-21 US claimed
CN-116806243-B Polyolefin-based diffuser for lighting fixtures 哈维尔印度有限公司 2024-10-15 CN claimed
CN-118176440-A Transparent optical article with improved blue light blocking capability and greater aesthetics 依视路国际公司 2024-06-11 CN claimed
CN-113504662-B Transparent optical article with colorless appearance 依视路国际公司 2024-04-09 CN claimed
CN-115073485-B 3-aryl-7, 8-pyranocoumarin derivative, and preparation method and application thereof 广西中医药大学 2024-02-23 CN claimed
CN-117327288-A Polyvinyl acetal resin powder, intermediate film and preparation method thereof 浙江德斯泰新材料股份有限公司 2024-01-02 CN claimed
CN-116806243-A Polyolefin-based diffuser for lighting fixtures 哈维尔印度有限公司 2023-09-26 CN claimed
WO-2023072963-A1 TRANSPARENT OPTICAL ARTICLE WITH INCREASED BLUE LIGHT CUTTING ABILITY AND SUPERIOR AESTHETICS ESSILOR INTERNATIONAL (FR) 2023-05-04 WO claimed
EP-4174532-A1 TRANSPARENT OPTICAL ARTICLE WITH INCREASED BLUE LIGHT CUTTING ABILITY AND SUPERIOR AESTHETICS Essilor International (FR) 2023-05-03 EP claimed
CN-115644433-A Application of phenyl coumarone KGM composition in inhibiting formation of gastrointestinal pentostatin 湖北工业大学 2023-01-31 CN claimed
EP-1125966-A1 White opaque, flame-retardant, UV-stabilized film with low transparency, made from a crystallizable thermoplastic polymer Mitsubishi Polyester Film GmbH (DE) 2001-08-22 EP claimed
EP-1125967-A1 White opaque film with low transparency, made from a crystallizable thermoplastic polymer Mitsubishi Polyester Film GmbH (DE) 2001-08-22 EP claimed
EP-1125968-A1 White opaque UV-stabilized film with low transparency, made from a crystallizable thermoplastic polymer Mitsubishi Polyester Film GmbH (DE) 2001-08-22 EP claimed
WO-2001055261-A2 AMORPHOUS, STRUCTURED, FLAME-INHIBITING UV LIGHT-ABSORBING FILM WHICH IS RENDERED OPAQUE BY DYING MITSUBISHI POLYESTER FILM GMBH (DE) 2001-08-02 WO claimed
WO-2001055246-A1 AMORPHOUS, STRUCTURED, UV LIGHT-ABSORBING FILM WHICH IS RENDERED OPAQUE BY DYING, A METHOD FOR THE PRODUCTION THEREOF AND ITS USE MITSUBISHI POLYESTER FILM GMBH (DE) 2001-08-02 WO claimed
WO-2001053403-A2 AMORPHOUS STRUCTURED TRANSPARENTLY-COLOURED UV-LIGHT ABSORBING FILM, METHOD FOR PRODUCTION AND THE USE THEREOF MITSUBISHI POLYESTER FILM GMBH (DE) 2001-07-26 WO claimed
WO-2001053402-A1 AMORPHOUS STRUCTURED TRANSPARENT UV-LIGHT ABSORBING FILM, METHOD FOR PRODUCTION AND THE USE THEREOF MITSUBISHI POLYESTER FILM GMBH (DE) 2001-07-26 WO claimed
US-5152922-A 1,4-DISTYRYLBENZENE COMPOUNDS AND MIXTURES THEREOF WITH OTHER 1,4-DISTYRYBENZENE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1992-10-06 US claimed
EP-0252009-B1 1,4-DISTYRYL BENZENE COMPOUNDS AND THEIR MIXTURES WITH OTHER 1,4-DISTYRYL BENZENE COMPOUNDS CIBA-GEIGY AG (CH) 1990-08-01 EP claimed
EP-0252009-A1 1,4-Distyryl benzene compounds and their mixtures with other 1,4-distyryl benzene compounds CIBA-GEIGY AG (CH) 1988-01-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137591-A1 COMPOSITIONS AND DEVICES FOR CONTAINING MEDICAL FLUIDS TFEB, LAGE3, RICTOR RAB9A 2768/4885KDM4E 64/4885MAOB 4139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.