Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22621489 | 0.85 | HDAC1 (0.72) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL20597404 | 0.83 | HDAC2 (0.73) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL1847911 | 0.81 | HDAC2 (1.00) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| Benzene SCHEMBL28125146 | 0.81 | HDAC2 (1.00) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL18813655 | 0.81 | PIN1 (0.51) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL353132 | 0.79 | HDAC2 (0.68) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL967387 | 0.79 | HDAC2 (0.68) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL9848998 | 0.79 | HDAC2 (0.68) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL622181 | 0.79 | HDAC2 (0.68) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL6290165 | 0.79 | HPGD (0.66) | HDAC2HDAC8HDAC6HDAC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |