Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19418905 | 0.86 | MAPT (0.56) | PIN1HDAC2HDAC8HDAC6ITGB3 | |
| SCHEMBL22361824 | 0.86 | MAPT (0.56) | PIN1HDAC2HDAC8HDAC6ITGB3 | |
| SCHEMBL18812968 | 0.85 | CASP1 (0.50) | HDAC2HDAC8HDAC6MAPTGAA | |
| SCHEMBL28680572 | 0.84 | ALDH1A1 (0.58) | PIN1HDAC2HDAC8HDAC6ITGB3 | |
| SCHEMBL5272643 | 0.84 | ALDH1A1 (0.58) | PIN1HDAC2HDAC8HDAC6ITGB3 | |
| SCHEMBL17537278 | 0.82 | PSMB5 (0.48) | PIN1HDAC2HDAC8HDAC6ITGB3 | |
| SCHEMBL24533898 | 0.81 | PIN1 (0.59) | PIN1HDAC2HDAC8HDAC6ITGB3 | |
| SCHEMBL4153095 | 0.81 | ITGB3 (0.65) | PIN1HDAC2HDAC8HDAC6ITGB3 | |
| SCHEMBL5458748 | 0.81 | ITGB3 (0.65) | PIN1HDAC2HDAC8HDAC6ITGB3 | |
| SCHEMBL4153101 | 0.81 | ITGB3 (0.65) | PIN1HDAC2HDAC8HDAC6ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988421-B2 | Dipeptides as inhibitors of human immunoproteasomes | CORNELL UNIVERSITY (US) | 2018-06-05 | — | — | US | disclosed |
| US-20170121366-A1 | DIPEPTIDES AS INHIBITORS OF HUMAN IMMUNOPROTEASOMES | CORNELL UNIVERSITY | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121366-A1 | DIPEPTIDES AS INHIBITORS OF HUMAN IMMUNOPROTEASOMES | DNPEP, PSMB10, DPEP1 | PIN1 769/4885HDAC2 1149/4885HDAC8 1345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.