Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 4/20 | 0.53 |
| ▸ | ERCC4 | Q92889 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GRK2 | P25098 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1623733 | 0.81 | ERCC1 (0.54) | ERCC1ERCC4ALDH1A1LMNAGAA | |
| SCHEMBL1561387 | 0.81 | MAPT (0.70) | ERCC1ERCC4ALDH1A1LMNAGAA | |
| SCHEMBL26345596 | 0.80 | MAPT (0.54) | ALDH1A1LMNAGAAKDM4EKMT2A | |
| SCHEMBL2318554 | 0.79 | L3MBTL1 (0.58) | ERCC1ERCC4ALDH1A1LMNAGAA | |
| SCHEMBL1174341 | 0.79 | PKM (0.56) | ERCC1ERCC4ALDH1A1LMNAGAA | |
| Hydrochloric Acid SCHEMBL11858514 | 0.79 | MAPT (0.68) | ERCC1ERCC4ALDH1A1LMNAGAA | |
| SCHEMBL30095424 | 0.78 | ABAT (0.50) | ERCC1ERCC4ALDH1A1LMNAGAA | |
| Hydrochloric Acid SCHEMBL3069393 | 0.78 | ABAT (0.53) | ERCC1ERCC4ALDH1A1LMNAGAA | |
| SCHEMBL1330698 | 0.78 | ABAT (0.53) | ERCC1ERCC4ALDH1A1LMNAGAA | |
| SCHEMBL7785939 | 0.78 | ABAT (0.53) | ERCC1ERCC4ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |