Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1689404 | 0.87 | HDAC3 (0.62) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A | |
| SCHEMBL23213561 | 0.86 | MEN1 (0.50) | ALDH1A1HSD17B10RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL19262164 | 0.82 | PTPRC (0.51) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A | |
| SCHEMBL505220 | 0.82 | RXFP1 (0.69) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2RXFP1 | |
| SCHEMBL30022965 | 0.82 | RXFP1 (0.69) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2RXFP1 | |
| SCHEMBL12655113 | 0.81 | POLB (0.57) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A | |
| SCHEMBL1901172 | 0.80 | ALDH1A1 (0.76) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A | |
| SCHEMBL27965723 | 0.80 | HSD17B10 (0.55) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A | |
| SCHEMBL9761962 | 0.79 | L3MBTL1 (0.61) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A | |
| SCHEMBL5536500 | 0.79 | L3MBTL1 (0.61) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095228-A1 | METHOD FOR THE PREPARATION OF ERLOTINIB | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095228-A1 | METHOD FOR THE PREPARATION OF ERLOTINIB | EGFR, ABL1, ERBB2 | ALDH1A1 823/4885HSD17B10 1509/4885CYP1A2 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.