Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22400614 | 0.84 | NOTUM (0.50) | NOTUMTDP1CA12CA1CA2 | |
| SCHEMBL839253 | 0.84 | NOTUM (0.59) | NOTUMCNR2SLC7A5TDP1CA12 | |
| SCHEMBL27802722 | 0.81 | NOTUM (0.53) | NOTUMCNR2TDP1CA12CA1 | |
| SCHEMBL25677270 | 0.80 | NOTUM (0.74) | NOTUMTDP1CA12CA1CA2 | |
| SCHEMBL24337485 | 0.78 | NOTUM (0.50) | NOTUMCNR2TDP1CA12CA1 | |
| SCHEMBL26334404 | 0.78 | NOTUM (0.53) | NOTUMCNR2SLC7A5TDP1CA12 | |
| SCHEMBL1495777 | 0.77 | NOTUM (0.49) | NOTUMSLC7A5TDP1CA12CA1 | |
| SCHEMBL184614 | 0.76 | NOTUM (0.67) | NOTUMTDP1CA12CA1CA2 | |
| Methyl 3,5-Dibromobenzoate SCHEMBL2408987 | 0.76 | NOTUM (0.67) | NOTUMCNR2TDP1CA12CA1 | |
| SCHEMBL1495639 | 0.76 | NOTUM (0.59) | NOTUMTDP1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331745-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | NOVO NORDISK AS (DK) | 2023-10-19 | — | — | US | disclosed |
| US-11767332-B2 | Glucose-sensitive albumin-binding derivatives | NOVO NORDISK A/S (DK) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331745-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | ALB, DBI, FABP4 | NOTUM 2218/4885CNR2 4233/4885SLC7A5 620/4885 |
| US-11767332-B2 | Glucose-sensitive albumin-binding derivatives | ALB, DBI, FABP4 | NOTUM 2218/4885CNR2 4233/4885SLC7A5 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.