Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.52 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16770015 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTTP53ALDH1A1GAA | |
| SCHEMBL1128988 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTTP53ALDH1A1GAA | |
| SCHEMBL26340909 | 0.81 | PDE5A (0.41) | SMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL26334877 | 0.80 | MEN1 (0.41) | SMN1; SMN2MAPTTP53ALDH1A1GAA | |
| SCHEMBL16770017 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTTP53ALDH1A1GAA | |
| SCHEMBL26334724 | 0.79 | PDE5A (0.41) | SMN1; SMN2TP53 | |
| SCHEMBL5544118 | 0.79 | MAPT (0.56) | SMN1; SMN2MAPTTP53ALDH1A1GAA | |
| SCHEMBL856450 | 0.78 | GABRA5 (0.61) | SMN1; SMN2MAPTTP53ALDH1A1GAA | |
| SCHEMBL7795327 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTTP53ALDH1A1GAA | |
| SCHEMBL26349082 | 0.78 | SLC6A3 (0.42) | SMN1; SMN2MAPTTP53ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |