Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26114501 | 0.74 | CMA1 (0.56) | GAALMNAHTTNPSR1CMA1 | |
| SCHEMBL17360667 | 0.74 | CMA1 (0.59) | GAALMNAHTTNPSR1CMA1 | |
| SCHEMBL26538697 | 0.73 | GAA (0.48) | GAALMNAHTTNPSR1CMA1 | |
| SCHEMBL26111496 | 0.72 | GAA (0.50) | GAALMNAHTTNPSR1CMA1 | |
| SCHEMBL26115953 | 0.72 | GAA (0.50) | GAALMNAHTTNPSR1CMA1 | |
| SCHEMBL26111499 | 0.72 | GAA (0.50) | GAALMNAHTTNPSR1CMA1 | |
| SCHEMBL27721848 | 0.71 | CMA1 (0.51) | GAALMNAHTTNPSR1CMA1 | |
| SCHEMBL32686312 | 0.70 | SMN1; SMN2 (0.43) | GAALMNAHTTNPSR1CMA1 | |
| SCHEMBL32686496 | 0.70 | POLB (0.44) | GAALMNAHTTNPSR1CMA1 | |
| SCHEMBL28946779 | 0.69 | ALDH1A1 (0.52) | GAALMNANPSR1CMA1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023170608-A1 | ACTIVATORS OF EFFECTOR T CELLS | ORUM THERAPEUTICS, INC. (KR) | 2023-09-14 | — | — | WO | disclosed |