Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27721848 | 0.84 | CMA1 (0.51) | GAACMA1GSK3AGSK3BGRM2 | |
| SCHEMBL26114501 | 0.79 | CMA1 (0.56) | GAACMA1GSK3AGSK3BGRM2 | |
| SCHEMBL17360667 | 0.75 | CMA1 (0.59) | GAACMA1GSK3AGSK3BGRM2 | |
| SCHEMBL26115953 | 0.74 | GAA (0.50) | GAACMA1GSK3AGSK3BGRM2 | |
| SCHEMBL26111499 | 0.74 | GAA (0.50) | GAACMA1GSK3AGSK3BGRM2 | |
| SCHEMBL26111496 | 0.74 | GAA (0.50) | GAACMA1GSK3AGSK3BGRM2 | |
| SCHEMBL26443937 | 0.73 | GAA (0.47) | GAACMA1GSK3AGSK3BGRM2 | |
| SCHEMBL26334885 | 0.73 | GAA (0.47) | GAACMA1GSK3AGSK3BGRM2 | |
| SCHEMBL26538695 | 0.72 | GSK3A (0.53) | GAACMA1GSK3AGSK3BGRM2 | |
| SCHEMBL6442206 | 0.71 | ADAM17 (0.56) | GAACMA1POLBCASP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4269387-A1 | PYRROLINONE COMPOUND AND SYNTHESIS METHOD THEREFOR | Poseidon Pharmaceutical Co., Ltd. (CN) | 2023-11-01 | — | — | EP | disclosed |
| US-20230322671-A1 | PYRROLINONE COMPOUND AND METHOD FOR PREPARING THE SAME | WUHAN JIANMIN DAPENG PHARMACEUTICAL CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
| US-20230322671-A1 | PYRROLINONE COMPOUND AND METHOD FOR PREPARING THE SAME | WUHAN JIANMIN DAPENG PHARMACEUTICAL CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322671-A1 | PYRROLINONE COMPOUND AND METHOD FOR PREPARING THE SAME | C1S, C5, SULT1A1 | GAA 4838/4885CMA1 2045/4885GSK3A 4872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.