SCHEMBL26335570

SCHEMBL26335570

CNC(=O)c1c(O)c(=O)oc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.56
CA9 Q16790 2/20 0.56
KDM4E B2RXH2 4/20 0.53
ALDH1A1 P00352 4/20 0.51
NQO1 P15559 4/20 0.51
LMNA P02545 3/20 0.51
MEN1 O00255 1/20 0.51
ABCB11 O95342 1/20 0.51
TP53 P04637 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
TSHR P16473 1/20 0.51
MAPK1 P28482 1/20 0.51
CYP2C19 P33261 1/20 0.51
KMT2A Q03164 1/20 0.51
PDE4D Q08499 1/20 0.51
PCSK7 Q16549 1/20 0.51
GPR35 Q9HC97 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17169389 0.88 CA12 (0.69) CA12CA9KDM4EALDH1A1NQO1
SCHEMBL26335692 0.83 CA12 (0.48) CA12CA9KDM4EALDH1A1NQO1
SCHEMBL26338052 0.81 CA12 (0.46) CA12CA9KDM4EALDH1A1NQO1
SCHEMBL1648026 0.80 CA12 (0.58) CA12CA9KDM4EALDH1A1NQO1
SCHEMBL3263341 0.79 CYP2C19 (0.58) KDM4EALDH1A1CYP2C9CYP2C19HPGD
SCHEMBL27543799 0.76 CA12 (0.54) CA12CA9KDM4EALDH1A1NQO1
SCHEMBL7737431 0.74 KDM4E (0.69) CA12CA9KDM4EALDH1A1NQO1
SCHEMBL29379994 0.74 KDM4E (0.69) CA12CA9KDM4EALDH1A1NQO1
SCHEMBL29872 0.74 KDM4E (0.69) CA12CA9KDM4EALDH1A1NQO1
SCHEMBL30153359 0.73 KDM4E (0.73) CA12CA9KDM4EALDH1A1NQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4249480-A1 DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Northwest A&F University (CN) 2023-09-27 EP disclosed