SCHEMBL26336151

SCHEMBL26336151

c1ccc(-c2c(-c3ccccc3)c3cc(N(c4ccccc4)c4ccc5c6ccccc6n(-c6ccc7ccccc7c6)c5c4)ccc3c3ccccc23)cc1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
F2 P00734 1/20 0.32
F10 P00742 1/20 0.32
PRSS1 P07477 1/20 0.32
KMT2A Q03164 1/20 0.31
HPGD P15428 1/20 0.31
MAPK9 P45984 2/20 0.30
MAPK10 P53779 2/20 0.30
MAPK8 P45983 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26336152 0.97 KDM4E (0.33) KDM4EATML3MBTL1F2F10
SCHEMBL26335231 0.97 KDM4E (0.35) KDM4EATML3MBTL1F2F10
SCHEMBL26336148 0.96 KDM4E (0.34) KDM4EATML3MBTL1F2F10
SCHEMBL26340241 0.95 KDM4E (0.32) KDM4EATML3MBTL1F2F10
SCHEMBL26336150 0.95 KDM4E (0.32) KDM4EATML3MBTL1F2F10
SCHEMBL26335233 0.94 KDM4E (0.31) KDM4EATML3MBTL1F2F10
SCHEMBL26337789 0.94 KDM4E (0.31) KDM4EATML3MBTL1F2F10
SCHEMBL26335234 0.94 F2 (0.33) KDM4EATML3MBTL1F2F10
SCHEMBL26340247 0.94 KDM4E (0.33) KDM4EATML3MBTL1F2F10
SCHEMBL26335219 0.92 KDM4E (0.35) KDM4EATML3MBTL1F2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301176-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENTS, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-21 US disclosed
US-20230301176-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENTS, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301176-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENTS, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE LEF1, ELAVL1, PIEZO1 KDM4E 1244/4885ATM 2812/4885L3MBTL1 452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.