Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14327576 | 0.82 | JAK2 (0.39) | JAK2 | |
| SCHEMBL14465247 | 0.79 | MEN1 (0.51) | — | |
| SCHEMBL2630113 | 0.74 | — | — | |
| SCHEMBL2633521 | 0.73 | — | — | |
| SCHEMBL2633717 | 0.73 | — | — | |
| SCHEMBL2630381 | 0.72 | — | — | |
| SCHEMBL8941819 | 0.71 | JAK2 (0.51) | JAK2 | |
| SCHEMBL14327598 | 0.71 | JAK2 (0.38) | JAK2 | |
| SCHEMBL8940073 | 0.70 | CCNT1 (0.68) | JAK2 | |
| SCHEMBL18629084 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163917-B2 | Azaindoles useful as inhibitors of Janus kinases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-04-24 | — | — | US | disclosed |