Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PRF1 | P14222 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26337411 | 0.84 | MAOA (0.38) | ALDH1A1MAPTSMN1; SMN2GAAMAOA | |
| SCHEMBL27655944 | 0.81 | MAOA (0.44) | ALDH1A1MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL27288131 | 0.80 | MAOA (0.42) | ALDH1A1MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL21063661 | 0.78 | MAOA (0.41) | ALDH1A1MAPTSMN1; SMN2KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL27286414 | 0.77 | MAOA (0.40) | ALDH1A1MAPTSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL28031186 | 0.75 | MAPT (0.44) | ALDH1A1MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL26421241 | 0.72 | SMN1; SMN2 (0.49) | ALDH1A1MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL26347539 | 0.71 | SMN1; SMN2 (0.41) | ALDH1A1MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL26339667 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL5540715 | 0.67 | MAOA (0.43) | ALDH1A1MAPTSMN1; SMN2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |