Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23818701 | 0.95 | POLRMT (0.32) | POLRMTDOT1L | |
| SCHEMBL23818824 | 0.95 | POLRMT (0.32) | POLRMTDOT1L | |
| SCHEMBL23819090 | 0.94 | POLRMT (0.31) | POLRMTDOT1L | |
| SCHEMBL26338991 | 0.93 | POLRMT (0.32) | POLRMTDOT1L | |
| SCHEMBL26332441 | 0.93 | JAK2 (0.32) | JAK2JAK1POLRMTPIK3CD | |
| SCHEMBL23819323 | 0.93 | JAK2 (0.32) | JAK2JAK1POLRMTPIK3CD | |
| SCHEMBL26338202 | 0.91 | POLRMT (0.33) | POLRMTDOT1L | |
| SCHEMBL23818579 | 0.91 | JAK2 (0.31) | JAK2JAK1POLRMT | |
| SCHEMBL23819091 | 0.91 | POLRMT (0.33) | POLRMTCSNK2A2CSNK2A1DOT1L | |
| SCHEMBL23819004 | 0.89 | POLRMT (0.32) | POLRMTDOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767337-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767337-B2 | Antiviral compounds | MAVS, HAVCR2, ZC3HAV1 | JAK2 2606/4885JAK1 4312/4885POLRMT 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.