Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 4/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 6/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28057447 | 0.80 | KDM4E (0.41) | HTTCCNCCDK8KDM4ECASP1 | |
| SCHEMBL20509797 | 0.78 | ICAM1 (0.43) | HTTCCNCCDK8KDM4EGPR139 | |
| SCHEMBL10857605 | 0.76 | DHODH (0.41) | HTTKDM4EXDHICAM1SELE | |
| SCHEMBL30753169 | 0.74 | MAPK1 (0.44) | HTTCDK8KDM4EICAM1SELE | |
| SCHEMBL26337401 | 0.74 | MAPK1 (0.44) | HTTCDK8KDM4EICAM1SELE | |
| SCHEMBL20509990 | 0.71 | ICAM1 (0.40) | HTTKDM4ETSHRICAM1SELE | |
| SCHEMBL162515 | 0.69 | ALOX5 (0.44) | HTTKDM4EALOX15TSHRCASP1 | |
| SCHEMBL25607337 | 0.69 | NAMPT (0.48) | HTTKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL23984472 | 0.68 | HDAC3 (0.66) | HTTKDM4EALOX15TSHRCASP1 | |
| SCHEMBL19759423 | 0.67 | ICAM1 (0.45) | HTTKDM4EGPR139ICAM1SELE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |