Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.40 |
| ▸ | SELE | P16581 | 4/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 4/20 | 0.37 |
| ▸ | PIM1 | P11309 | 4/20 | 0.37 |
| ▸ | PRKACA | P17612 | 4/20 | 0.37 |
| ▸ | KDR | P35968 | 4/20 | 0.37 |
| ▸ | GSK3A | P49840 | 4/20 | 0.37 |
| ▸ | GSK3B | P49841 | 4/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753169 | 1.00 | MAPK1 (0.44) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10857605 | 0.84 | DHODH (0.41) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL20509797 | 0.82 | ICAM1 (0.43) | ALDH1A1MAPTTDP1ICAM1SELE | |
| SCHEMBL28057447 | 0.78 | KDM4E (0.41) | MAPK1ALDH1A1MEN1KMT2AICAM1 | |
| SCHEMBL26339565 | 0.74 | HTT (0.43) | ALDH1A1MAPTICAM1SELEVCAM1 | |
| SCHEMBL827310 | 0.74 | ALDH1A1 (0.47) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30745208 | 0.74 | ALDH1A1 (0.47) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8881790 | 0.72 | CYP2A6 (0.51) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL8882792 | 0.72 | CYP2A6 (0.51) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL3597257 | 0.71 | MEN1 (0.44) | MAPK1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |