Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.72 |
| ▸ | APLNR | P35414 | 1/20 | 0.72 |
| ▸ | CCR6 | P51684 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16112358 | 0.85 | LMNA (0.72) | LMNAALDH1A1SMN1; SMN2CXCR5APLNR | |
| SCHEMBL26341512 | 0.84 | LMNA (1.00) | LMNAALDH1A1SMN1; SMN2CXCR5APLNR | |
| SCHEMBL26341663 | 0.82 | LMNA (0.72) | LMNAALDH1A1SMN1; SMN2CXCR5APLNR | |
| SCHEMBL26341361 | 0.81 | LMNA (0.70) | LMNAALDH1A1SMN1; SMN2CXCR5APLNR | |
| SCHEMBL26341752 | 0.80 | LMNA (0.70) | LMNAALDH1A1SMN1; SMN2CXCR5APLNR | |
| SCHEMBL28203159 | 0.78 | ALDH1A1 (0.67) | LMNAALDH1A1SMN1; SMN2CXCR5APLNR | |
| SCHEMBL3260907 | 0.78 | ALDH1A1 (0.67) | LMNAALDH1A1SMN1; SMN2CXCR5APLNR | |
| SCHEMBL26341328 | 0.78 | LMNA (0.70) | LMNAALDH1A1SMN1; SMN2CXCR5APLNR | |
| SCHEMBL27171248 | 0.77 | ALDH1A1 (0.68) | LMNAALDH1A1SMN1; SMN2CXCR5APLNR | |
| SCHEMBL26341719 | 0.77 | ALDH1A1 (0.68) | LMNAALDH1A1SMN1; SMN2CXCR5APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |