Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 8/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 5/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.36 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29588123 | 0.84 | P2RX3 (0.39) | P2RX3IDH1 | |
| SCHEMBL26344155 | 0.84 | P2RX3 (0.39) | P2RX3IDH1 | |
| SCHEMBL26344057 | 0.82 | PDE9A (0.47) | P2RX3PDE9A | |
| SCHEMBL26344200 | 0.82 | IDH1 (0.38) | IDH1PDE9A | |
| SCHEMBL26344076 | 0.79 | P2RX3 (0.45) | P2RX3CYP3A4CYP2B6IDH1PDE9A | |
| SCHEMBL26346334 | 0.76 | P2RX3 (0.39) | P2RX3 | |
| SCHEMBL26344153 | 0.76 | P2RX3 (0.39) | P2RX3PDE9A | |
| SCHEMBL26344050 | 0.73 | IDH1 (0.52) | IDH1 | |
| SCHEMBL26343466 | 0.73 | KDM4E (0.42) | LYNPPARG | |
| SCHEMBL29588283 | 0.70 | CYP3A4 (0.40) | P2RX3CYP3A4CYP2B6PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249474-A1 | TRIAZINE DIONE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-09-27 | — | — | EP | disclosed |