Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 6/20 | 0.52 |
| ▸ | DUT | P33316 | 7/20 | 0.51 |
| ▸ | SOS1 | Q07889 | 6/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26344032 | 0.84 | ACACB (0.41) | IDH1DUTSOS1ACACB | |
| SCHEMBL29589354 | 0.84 | ACACB (0.41) | IDH1DUTSOS1ACACB | |
| SCHEMBL29589397 | 0.84 | ACACB (0.41) | IDH1DUTSOS1ACACB | |
| SCHEMBL26344040 | 0.84 | ACACB (0.41) | IDH1DUTSOS1ACACB | |
| SCHEMBL26344024 | 0.84 | ACACB (0.41) | IDH1DUTSOS1ACACB | |
| SCHEMBL26344046 | 0.83 | DUT (0.43) | IDH1DUTACACB | |
| SCHEMBL26344076 | 0.77 | P2RX3 (0.45) | IDH1DUTSOS1 | |
| SCHEMBL26344029 | 0.77 | ACACB (0.39) | IDH1DUTSOS1ACACB | |
| SCHEMBL15247551 | 0.74 | DUT (0.51) | IDH1DUTSOS1ACACB | |
| SCHEMBL26344061 | 0.73 | P2RX3 (0.38) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249474-A1 | TRIAZINE DIONE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-09-27 | — | — | EP | disclosed |