SCHEMBL26344223

SCHEMBL26344223

c1ccc(-n2c(-c3ccc(-c4c5ccccc5c(-c5ccccc5-c5ccncc5)c5ccccc45)cc3)nc3ccccc32)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
HSP90AA1 P07900 1/20 0.51
MAPT P10636 1/20 0.51
ALDH1A1 P00352 5/20 0.49
ESR1 P03372 2/20 0.48
ESR2 Q92731 2/20 0.48
RECQL P46063 1/20 0.45
GRIA1 P42261 1/20 0.44
CACNG8 Q8WXS5 1/20 0.44
CACNG2 Q9Y698 1/20 0.44
MDM2 Q00987 1/20 0.43
KCNH2 Q12809 1/20 0.43
AOC3 Q16853 1/20 0.43
HTT P42858 2/20 0.42
MAPK1 P28482 2/20 0.42
PTGS2 P35354 1/20 0.41
RAB9A P51151 1/20 0.40
AKT1 P31749 1/20 0.39
PRKACA P17612 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26344220 0.97 ESR1 (0.53) MEN1KMT2AHSP90AA1MAPTALDH1A1
SCHEMBL26344558 0.94 MEN1 (0.49) MEN1KMT2AHSP90AA1MAPTALDH1A1
SCHEMBL26344219 0.93 RECQL (0.52) MEN1KMT2AHSP90AA1MAPTALDH1A1
SCHEMBL18999469 0.93 ESR1 (0.56) MEN1KMT2AHSP90AA1MAPTALDH1A1
SCHEMBL25668052 0.93 MEN1 (0.58) MEN1KMT2AHSP90AA1MAPTALDH1A1
SCHEMBL26345090 0.92 RECQL (0.48) MEN1KMT2AHSP90AA1MAPTALDH1A1
SCHEMBL26344564 0.92 MEN1 (0.60) MEN1KMT2AHSP90AA1MAPTALDH1A1
SCHEMBL2604830 0.90 ESR1 (0.59) MEN1KMT2AHSP90AA1MAPTALDH1A1
SCHEMBL26344221 0.90 MEN1 (0.46) MEN1KMT2AHSP90AA1MAPTALDH1A1
SCHEMBL26344226 0.90 MEN1 (0.46) MEN1KMT2AHSP90AA1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, OR10J3, TMEM109 MEN1 480/4885KMT2A 1864/4885HSP90AA1 3977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.