Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | IDE | P14735 | 2/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | F13A1 | P00488 | 3/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BHMT | Q93088 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2634170 | 1.00 | ABL1 (0.37) | ABL1IDERIN1PPARGNR2E3 | |
| SCHEMBL11886046 | 0.80 | MAP3K14 (0.33) | SMN1; SMN2LMNADDB1CRBN | |
| SCHEMBL24756756 | 0.80 | ALDH1A1 (0.42) | SMN1; SMN2LMNADDB1CRBNL3MBTL1 | |
| SCHEMBL10489330 | 0.80 | ALDH1A1 (0.42) | SMN1; SMN2LMNADDB1CRBNL3MBTL1 | |
| SCHEMBL18888757 | 0.78 | NPC1 (0.41) | SMN1; SMN2LMNADDB1CRBNL3MBTL1 | |
| SCHEMBL27111821 | 0.76 | SMN1; SMN2 (0.36) | SMN1; SMN2TDP1DDB1CRBNL3MBTL1 | |
| SCHEMBL22765599 | 0.76 | LMNA (0.39) | LMNADDB1CRBN | |
| Octanedioate SCHEMBL6037701 | 0.76 | TSHR (0.43) | ABL1IDERIN1PPARGNR2E3 | |
| SCHEMBL9289932 | 0.75 | PTGIR (0.40) | PPARGPTGIRLMNATSHRNFKB1 | |
| SCHEMBL24885111 | 0.74 | ABL1 (0.47) | ABL1IDERIN1PPARGNR2E3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2437786-B1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | YEDA RES & DEV (IL) | 2016-05-18 | — | — | EP | disclosed |
| US-20150093370-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-04-02 | — | — | US | disclosed |
| US-20150093370-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-04-02 | — | — | US | disclosed |
| US-20120134977-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2012-05-31 | — | — | US | disclosed |
| US-20120134977-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2012-05-31 | — | — | US | disclosed |
| EP-2437786-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | Yeda Research and Development Co. Ltd. (IL) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010140148-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | YEDA RESEARCH AND DEVELOPMENT CO . LTD (IL) | 2010-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120134977-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | ALB, DNPEP, CNDP2 | ABL1 113/4885IDE 757/4885RIN1 3111/4885 |
| US-20150093370-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | ALB, DNPEP, CNDP2 | ABL1 113/4885IDE 757/4885RIN1 3111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.