SCHEMBL26344387

SCHEMBL26344387

CCc1nc2ccccc2n1-c1ccc2cc(-c3c4ccccc4c(-c4cccc(-c5ccncc5)c4)c4ccccc34)ccc2c1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.43
MAPK10 P53779 6/20 0.40
MAPK9 P45984 4/20 0.40
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
HSP90AA1 P07900 1/20 0.38
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
PDE10A Q9Y233 2/20 0.37
CYP1A2 P05177 1/20 0.37
MAPK8 P45983 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26344575 0.95 MAPT (0.43) MAPTMAPK10MAPK9MEN1KMT2A
SCHEMBL26343760 0.94 MAPT (0.43) MAPTMAPK10MEN1KMT2AKDM4E
SCHEMBL26344367 0.93 MAPT (0.42) MAPTMEN1KMT2AHSP90AA1KDM4E
SCHEMBL26344383 0.93 MAPT (0.42) MAPTMEN1KMT2AHSP90AA1KDM4E
SCHEMBL26344577 0.92 PDE10A (0.41) MAPTMEN1KMT2AHSP90AA1KDM4E
SCHEMBL26344361 0.92 MAPT (0.40) MAPTMEN1KMT2AHSP90AA1KDM4E
SCHEMBL26344393 0.92 MAPT (0.40) MAPTMEN1KMT2AHSP90AA1KDM4E
SCHEMBL24674421 0.91 MAPT (0.40) MAPTMAPK10MEN1KMT2AKDM4E
SCHEMBL26344517 0.90 MAPT (0.51) MAPT
SCHEMBL26343687 0.90 MAPT (0.43) MAPTMAPK10MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, OR10J3, TMEM109 MAPT 1419/4885MAPK10 1684/4885MAPK9 396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.