SCHEMBL26344494

SCHEMBL26344494

CCc1nc2ccccc2n1-c1cccc(-c2c3ccccc3c(-c3cccc(-c4cccnc4)c3)c3ccccc23)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.46
CYP11B2 P19099 4/20 0.40
NOS2 P35228 1/20 0.39
EGFR P00533 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
GSR P00390 1/20 0.39
GABRA1 P14867 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
GABRA2 P47869 1/20 0.38
ALOX12 P18054 1/20 0.38
CYP11B1 P15538 2/20 0.38
MDM2 Q00987 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26344519 1.00 MAPT (0.46) MAPTCYP11B2NOS2EGFRKDM4E
SCHEMBL26344553 0.97 MAPT (0.43) MAPTCYP11B2NOS2EGFRGABRA1
SCHEMBL26344521 0.95 MAPT (0.45) MAPTCYP11B2NOS2KDM4EMEN1
SCHEMBL26344498 0.93 MAPT (0.45) MAPTCYP11B2EGFRKDM4EMEN1
SCHEMBL26344517 0.92 MAPT (0.51) MAPTCYP11B2NOS2CYP11B1
SCHEMBL26344513 0.92 MAPT (0.44) MAPTCYP11B2EGFRMEN1KMT2A
SCHEMBL26344423 0.91 MAPT (0.46) MAPTCYP11B2NOS2KDM4EMEN1
SCHEMBL26345086 0.91 MAPT (0.42) MAPTCYP11B2NOS2EGFRKDM4E
SCHEMBL26343767 0.89 MEN1 (0.46) MAPTKDM4EMEN1ALDH1A1HPGD
SCHEMBL26343498 0.89 MEN1 (0.46) MAPTKDM4EMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, OR10J3, TMEM109 MAPT 1419/4885CYP11B2 2732/4885NOS2 2152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.