SCHEMBL26344499

SCHEMBL26344499

c1ccc(-n2c(-c3ccccc3-c3c4ccccc4c(-c4cccc(-c5cccnc5)c4)c4ccccc34)nc3ccccc32)cc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.47
RECQL P46063 1/20 0.44
AOC3 Q16853 1/20 0.42
G6PD P11413 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
CYP11B2 P19099 1/20 0.41
MDM2 Q00987 1/20 0.40
AKT1 P31749 2/20 0.39
AKT2 P31751 2/20 0.39
RAB9A P51151 1/20 0.39
DHODH Q02127 1/20 0.39
GSR P00390 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26344428 0.92 MAPT (0.52) MAPTRECQLAOC3G6PDESR1
SCHEMBL26344525 0.92 RECQL (0.46) MAPTRECQLAOC3G6PDESR1
SCHEMBL26344501 0.91 MAPT (0.53) MAPTAOC3G6PDESR1ESR2
SCHEMBL26345103 0.91 MAPT (0.50) MAPTAOC3G6PDESR1ESR2
SCHEMBL26344425 0.90 RECQL (0.51) MAPTRECQLAOC3G6PDESR1
SCHEMBL26343735 0.90 RECQL (0.50) MAPTRECQLESR1ESR2RAB9A
SCHEMBL26344371 0.89 MEN1 (0.46) MAPTRECQLAOC3ESR1ESR2
SCHEMBL26344503 0.89 MAPT (0.51) MAPTAOC3G6PDESR1ESR2
SCHEMBL26344507 0.88 MAPT (0.54) MAPTAOC3G6PDESR1ESR2
SCHEMBL26344433 0.88 MAPT (0.54) MAPTRECQLAOC3G6PDESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, OR10J3, TMEM109 MAPT 1419/4885RECQL 2039/4885AOC3 111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.