SCHEMBL26344965

SCHEMBL26344965

CC1(C)c2ccccc2-c2ccc(-c3c4ccccc4c(-c4nc5ccccc5n4-c4ccccc4)c4ccccc34)cc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.42
HTT P42858 2/20 0.41
MAPK1 P28482 2/20 0.41
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
PTGER4 P35408 1/20 0.39
ATR Q13535 1/20 0.37
PRKACA P17612 1/20 0.37
RPS6KB1 P23443 1/20 0.37
GSK3B P49841 1/20 0.37
ROCK1 Q13464 1/20 0.37
GRIA1 P42261 1/20 0.37
CACNG8 Q8WXS5 1/20 0.37
CACNG2 Q9Y698 1/20 0.37
GSR P00390 1/20 0.36
SIRT2 Q8IXJ6 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
ALDH1A1 P00352 2/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC8 Q9BY41 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12247137 0.96 RECQL (0.39) RECQLHTTMAPK1ESR1ESR2
SCHEMBL13488182 0.96 RECQL (0.39) RECQLHTTMAPK1ESR1ESR2
SCHEMBL24811914 0.95 ESR1 (0.44) RECQLHTTMAPK1ESR1ESR2
SCHEMBL13487845 0.94 RECQL (0.38) RECQLHTTMAPK1ESR1ESR2
SCHEMBL13487936 0.94 RECQL (0.38) RECQLHTTMAPK1ESR1ESR2
SCHEMBL26343698 0.94 RECQL (0.43) RECQLHTTMAPK1ESR1ESR2
SCHEMBL13487787 0.93 RECQL (0.38) RECQLHTTMAPK1ESR1ESR2
SCHEMBL26343703 0.93 ESR1 (0.42) RECQLHTTMAPK1ESR1ESR2
SCHEMBL12246938 0.92 PTGER4 (0.41) RECQLHTTMAPK1ESR1ESR2
SCHEMBL21392554 0.92 ESR1 (0.48) RECQLHTTMAPK1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, OR10J3, TMEM109 RECQL 2039/4885HTT 2655/4885MAPK1 675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.