SCHEMBL26345166

SCHEMBL26345166

CCc1nc2ccccc2n1-c1c2ccccc2c(-c2cccc(-c3ccccc3)c2)c2cc(-c3ccccc3)ccc12

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 1/20 0.43
PPARG P37231 1/20 0.39
RECQL P46063 1/20 0.38
PTGER4 P35408 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPY5R Q15761 1/20 0.36
TP53 P04637 1/20 0.36
TSPO P30536 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26345167 0.95 KDM4E (0.45) MAPTKDM4EMEN1ALDH1A1HPGD
SCHEMBL26344940 0.95 MAPT (0.47) MAPTKDM4EMEN1ALDH1A1HPGD
SCHEMBL26367825 0.90 MAPT (0.39) MAPTKDM4EMEN1ALDH1A1HPGD
SCHEMBL24674239 0.90 KDM4E (0.43) MAPTKDM4EMEN1ALDH1A1HPGD
SCHEMBL24674436 0.90 KDM4E (0.43) MAPTKDM4EMEN1ALDH1A1HPGD
SCHEMBL24674451 0.90 KDM4E (0.43) MAPTKDM4EMEN1ALDH1A1HPGD
SCHEMBL24673733 0.90 KDM4E (0.43) MAPTKDM4EMEN1ALDH1A1HPGD
SCHEMBL24674456 0.90 KDM4E (0.43) MAPTKDM4EMEN1ALDH1A1HPGD
SCHEMBL26345331 0.90 MEN1 (0.43) MAPTKDM4EMEN1ALDH1A1HPGD
SCHEMBL26345208 0.90 MEN1 (0.43) MAPTKDM4EMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, OR10J3, TMEM109 MAPT 1419/4885KDM4E 3490/4885MEN1 480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.