SCHEMBL26348689

SCHEMBL26348689

CC(=O)CCCCCC(=O)N[C@@H](CCC(=O)O)C(=O)NCCOCCON

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.55
▸ NMT2 O60551 1/20 0.41
▸ NMT1 P30419 1/20 0.41
▸ FOLH1 Q04609 1/20 0.39
▸ LPAR3 Q9UBY5 3/20 0.38
▸ TLR2 O60603 1/20 0.38
▸ ITGB3 P05106 1/20 0.38
▸ ITGA2B P08514 1/20 0.38
▸ LPAR1 Q92633 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26348694 0.91 GLP1R (0.66) GLP1RLPAR3TLR2LPAR1
SCHEMBL24891111 0.84 GLP1R (0.63) GLP1RNMT2NMT1
SCHEMBL13184776 0.82 GLP1R (0.54) GLP1RNMT2NMT1FOLH1
SCHEMBL14998213 0.82 GLP1R (0.57) GLP1RNMT2NMT1LPAR3LPAR1
SCHEMBL13184781 0.81 GLP1R (0.53) GLP1RNMT2NMT1
SCHEMBL12660092 0.81 GLP1R (0.61) GLP1RFOLH1
SCHEMBL18552076 0.80 GLP1R (0.75) GLP1RLPAR3TLR2LPAR1
SCHEMBL27410264 0.80 GLP1R (0.52) GLP1RNMT2NMT1FOLH1
SCHEMBL12673878 0.80 GLP1R (0.52) GLP1RFOLH1
SCHEMBL19723974 0.79 GLP1R (0.74) GLP1RLPAR3TLR2LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230302150-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF AMBRX, INC. (US) 2023-09-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230302150-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF TLR3, TLR1, TLR9 GLP1R 319/4885NMT2 1805/4885NMT1 1960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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