Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | STAMBP | O95630 | 1/20 | 0.41 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13552144 | 0.88 | ALPL (0.46) | HPGDSLRRK2TRPV1ALPLCYP17A1 | |
| SCHEMBL1644022 | 0.86 | MGAM (0.57) | TRPV1PSMD14ALPLMGAMEPHX2 | |
| SCHEMBL7449066 | 0.85 | KMT2A (0.47) | HPGDSPSMD14STAMBPCOPS5MGAM | |
| SCHEMBL5405254 | 0.82 | HPGDS (0.55) | HPGDSPSMD14STAMBPCOPS5ALPL | |
| SCHEMBL15125086 | 0.80 | HPGDS (0.54) | HPGDSPSMD14STAMBPCOPS5ALPL | |
| SCHEMBL1644595 | 0.79 | MAOB (0.54) | TRPV1 | |
| SCHEMBL4548632 | 0.78 | SCN10A (0.42) | LRRK2TRPV1SCN10A | |
| SCHEMBL2627053 | 0.77 | LCK (0.56) | LRRK2CYP17A1CYP3A4EPHX2NR1H4 | |
| SCHEMBL15775057 | 0.76 | ALPL (0.50) | HPGDSPSMD14STAMBPCOPS5ALPL | |
| SCHEMBL3868878 | 0.76 | HPGDS (0.50) | HPGDSPSMD14STAMBPCOPS5ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303562-A1 | PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303562-A1 | PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP51A1, CYP4F11, WEE1 | HPGDS 1294/4885LRRK2 3462/4885TRPV1 2224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.