Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 18/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 13/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 11/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14642670 | 0.79 | S1PR3 (0.46) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL13471220 | 0.75 | SLC2A1 (0.47) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL13469385 | 0.73 | S1PR1 (0.41) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL13464618 | 0.72 | S1PR1 (0.39) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL13464647 | 0.72 | S1PR1 (0.39) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL13469236 | 0.72 | S1PR1 (0.40) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL13469327 | 0.72 | S1PR1 (0.40) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL2635388 | 0.72 | S1PR3 (0.45) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL14642940 | 0.71 | S1PR3 (0.50) | S1PR3 | |
| SCHEMBL16026090 | 0.69 | HDAC1 (0.44) | S1PR3S1PR1S1PR2S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130018019-A1 | AROMATIC COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHONATE (S1P) RECEPTOR ACTIVITY | ALLERGAN, INC. (US) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018019-A1 | AROMATIC COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHONATE (S1P) RECEPTOR ACTIVITY | S1PR1, S1PR3, S1PR2 | S1PR3 2/4885S1PR1 1/4885S1PR2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.