SCHEMBL263573

SCHEMBL263573

COC(=O)c1ccc(C(=O)O)cc1N

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 12/20 0.80
GAA P10253 10/20 0.80
ALDH1A1 P00352 9/20 0.80
HPGD P15428 6/20 0.80
MAPT P10636 6/20 0.80
HSD17B10 Q99714 5/20 0.80
GLA P06280 3/20 0.80
CASP1 P29466 1/20 0.80
CASP7 P55210 1/20 0.80
ATM Q13315 1/20 0.80
ABL1 P00519 1/20 0.62
CFTR P13569 2/20 0.57
PTGER4 P35408 1/20 0.51
GFER P55789 3/20 0.50
THRB P10828 3/20 0.50
HTT P42858 1/20 0.50
PLEC Q15149 1/20 0.50
NPC1 O15118 4/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
RAB9A P51151 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29867769 1.00 KDM4E (0.80) KDM4EGAAALDH1A1HPGDMAPT
SCHEMBL29358 0.89 KDM4E (1.00) KDM4EGAAALDH1A1HPGDMAPT
Hydrochloric Acid SCHEMBL2278703 0.87 KDM4E (0.96) KDM4EGAAALDH1A1HPGDMAPT
SCHEMBL2722810 0.86 KDM4E (0.60) KDM4EGAAALDH1A1HPGDMAPT
SCHEMBL22104116 0.86 KDM4E (0.80) KDM4EGAAALDH1A1HPGDMAPT
SCHEMBL3174910 0.86 KDM4E (0.80) KDM4EGAAALDH1A1HPGDMAPT
SCHEMBL1462210 0.86 KDM4E (0.80) KDM4EGAAALDH1A1HPGDMAPT
SCHEMBL16353322 0.84 KDM4E (0.83) KDM4EGAAALDH1A1HPGDMAPT
SCHEMBL22282986 0.84 KDM4E (0.56) KDM4EGAAALDH1A1HPGDMAPT
SCHEMBL29699657 0.83 KDM4E (0.55) KDM4EGAAALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111320761-B Metal organic framework nano composite material and preparation method and application thereof 南通大学 2021-12-10 CN claimed
CN-111320761-A Metal organic framework nano composite material and preparation method and application thereof 南通大学 2020-06-23 CN claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
WO-2025059562-A1 SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME ATAVISTIK BIO, INC. (US) 2025-03-20 WO disclosed
CN-111790388-B Photocatalyst and preparation method and application thereof 广州大学 2022-08-23 CN disclosed
CN-111116494-B Amide compounds containing quinazolinedione structure, preparation method and application thereof 江苏中旗科技股份有限公司 2022-08-16 CN disclosed
CN-111320761-B Metal organic framework nano composite material and preparation method and application thereof 南通大学 2021-12-10 CN disclosed
CN-212540320-U Acidimeter is used in amino-p-dimethyl ester production 上海霁翔生物医药有限公司 2021-02-12 CN disclosed
WO-2020225285-A1 PDEDELTA INHIBITORS UNIVERSITÉ DU LUXEMBOURG (LU) 2020-11-12 WO disclosed
CN-111320761-A Metal organic framework nano composite material and preparation method and application thereof 南通大学 2020-06-23 CN disclosed
CN-111116494-A Amide compounds containing quinazolinedione structure, preparation method and application thereof 江苏中旗科技股份有限公司 2020-05-08 CN disclosed
EP-0058924-A1 Process for the preparation of alkylesters of aromatic aminocarboxylic acids HOECHST AKTIENGESELLSCHAFT (DE) 1982-09-01 EP disclosed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US disclosed
US-4260540-A SPIN DYEING POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed
US-4246401-A Axomethine pigments BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
US-4014863-A LACQUERS, PRINTING INKS, PAINTS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed
US-3985711-A Dicarboxylic compounds having 2,4-quinazolinedione rings and polyester resins derived therefrom INSTITUT FRANCAIS DU PETROLE, DES CARBURANTS ET LUBRIFIANTS ET ENTREPRISE DE RECHERCHES ET D'ACTIVITIES PETROLIERES ELF (FR) 1976-10-12 US disclosed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed
US-3970630-A 2,4-Quinazoline dione-polyamide-ester resins INSTITUT FRANCAIS DU PETROLE, ES CARBURANTS ET LUBRIFIANTS ET ENTREPRISE DE RECHERCHES ET D'ACTIVITIES PETROLIERS ELF (FR) 1976-07-20 US disclosed