SCHEMBL29358

SCHEMBL29358

COC(=O)c1ccc(C(=O)OC)c(N)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 13/20 1.00
ALDH1A1 P00352 10/20 1.00
HPGD P15428 7/20 1.00
MAPT P10636 6/20 1.00
HSD17B10 Q99714 4/20 1.00
GAA P10253 4/20 1.00
GLA P06280 2/20 1.00
CASP1 P29466 1/20 1.00
CASP7 P55210 1/20 1.00
ATM Q13315 1/20 1.00
ABL1 P00519 1/20 0.66
CFTR P13569 2/20 0.60
NPC1 O15118 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
RAB9A P51151 2/20 0.58
NPSR1 Q6W5P4 2/20 0.58
USP2 O75604 1/20 0.57
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2278703 0.98 KDM4E (0.96) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL16353322 0.91 KDM4E (0.83) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL1462210 0.89 KDM4E (0.80) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL3174910 0.89 KDM4E (0.80) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL29867769 0.89 KDM4E (0.80) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL12042607 0.89 KDM4E (0.80) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL263573 0.89 KDM4E (0.80) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL161112 0.89 KDM4E (0.80) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL22104116 0.89 KDM4E (0.80) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL27470553 0.87 KDM4E (0.77) KDM4EALDH1A1HPGDMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 758 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651988-A1 METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS ExxonMobil Technology and Engineering Company (US) 2025-11-26 EP claimed
CN-119746656-A Preparation method of positively charged nanofiltration membrane, nanofiltration membrane and application of nanofiltration membrane 东莞市创明电池技术有限公司 2025-04-04 CN claimed
CN-119101935-A Platinum-based self-supporting membrane catalyst, preparation method and application thereof in electrocatalytic hydrogen evolution 南通大学 2024-12-10 CN claimed
US-20240300983-A1 Method of Making Metal-Organic Frameworks With a Precursor and Crystallization Aid EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) 2024-09-12 US claimed
US-20240254148-A1 METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) 2024-08-01 US claimed
WO-2024155562-A1 METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS ExxonMobil Technology and Engineering Company (US) 2024-07-25 WO claimed
CN-118026872-A 2-Amino dimethyl terephthalate eutectic and preparation method thereof 天津大学 2024-05-14 CN claimed
CN-118026870-A 2-Amino dimethyl terephthalate-tetracyanobenzene eutectic crystal and preparation method and application thereof 天津大学 2024-05-14 CN claimed
EP-4363100-A1 METHOD OF MAKING METAL-ORGANIC FRAMEWORKS WITH A PRECURSOR AND CRYSTALLIZATION AID ExxonMobil Technology and Engineering Company (US) 2024-05-08 EP claimed
CN-117986511-A Quaternary ammonium type covalent organic framework compound and preparation method of anion exchange membrane thereof 大连理工大学 2024-05-07 CN claimed
CN-106045868-A Method for producing dimethyl aminoterephthalate through catalytic hydrogenation 济南和润化工科技有限公司 2016-10-26 CN claimed
CN-104072403-B A kind of method preparing compound UNC1215 CHENGDU UNIVERSITY (CN) 2016-04-13 CN claimed
CN-103275518-B Method for preparing high-transparency high-strength pigment yellow 155 for water-based ink and water-based paint ANSHAN HIFICHEM CO., LTD. (CN) 2014-10-08 CN claimed
CN-104072403-A Method for preparing compound UNC1215 UNIV CHENGDU 2014-10-01 CN claimed
CN-103275518-A Method for preparing high-transparency high-strength pigment yellow 155 for water-based ink and water-based paint ANSHAN HIFICHEM CO LTD 2013-09-04 CN claimed
CN-1765961-A Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2006-05-03 CN claimed
US-6548647-B2 Spraying coupling components in solution or suspension to collide in reactor chamber, then pressurizing to remove; useful for offset printing inks CLARIANT GMBH (DE) 2003-04-15 US claimed
US-20020055619-A1 Process for preparing azo colorants CLARIANT GMBH 2002-05-09 US claimed
EP-1195411-A1 Process for the preparation of azo colourants Clariant GmbH (DE) 2002-04-10 EP claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254148-A1 METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS HCAR3, POF1B, HCAR1 KDM4E 3465/4885ALDH1A1 363/4885HPGD 160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.