SCHEMBL29699657

SCHEMBL29699657

COC(=O)c1ccc(C(=O)O)cc1C(=O)OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.55
ALDH1A1 P00352 4/20 0.55
HSD17B10 Q99714 3/20 0.55
HPGD P15428 3/20 0.55
ATM Q13315 3/20 0.55
GAA P10253 3/20 0.55
GLA P06280 2/20 0.55
MAPT P10636 1/20 0.55
CASP1 P29466 1/20 0.55
CASP7 P55210 1/20 0.55
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA12 O43570 3/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
CA14 Q9ULX7 3/20 0.50
KDM6B O15054 1/20 0.50
KDM5C P41229 1/20 0.50
KDM4C Q9H3R0 1/20 0.50
KDM2A Q9Y2K7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820141 1.00 KDM4E (0.55) KDM4EALDH1A1HSD17B10HPGDATM
SCHEMBL5834949 0.94 KDM4E (0.50) KDM4EALDH1A1HSD17B10HPGDATM
SCHEMBL293611 0.94 KDM4E (0.55) KDM4EALDH1A1HSD17B10HPGDATM
SCHEMBL293610 0.94 KDM4E (0.53) KDM4EALDH1A1HSD17B10HPGDATM
SCHEMBL17893501 0.88 KDM4E (0.47) KDM4EALDH1A1HSD17B10HPGDATM
SCHEMBL126043 0.88 KDM4E (0.69) KDM4EALDH1A1HSD17B10HPGDATM
SCHEMBL29492994 0.88 KDM4E (0.69) KDM4EALDH1A1HSD17B10HPGDATM
SCHEMBL9080431 0.86 KDM4E (0.62) KDM4EALDH1A1HSD17B10HPGDATM
SCHEMBL30967314 0.86 KDM4E (0.62) KDM4EALDH1A1HSD17B10HPGDATM
SCHEMBL3767347 0.86 KDM4E (0.62) KDM4EALDH1A1HSD17B10HPGDATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220170904-A1 SYSTEMS AND METHODS FOR MONITORING BIOLOGICAL TISSUE DEGRADATION ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2022-06-02 US disclosed