SCHEMBL26357467

SCHEMBL26357467

Cc1ccc(S(=O)(=O)c2ccc(-c3nc4ccc(-c5ccc6[nH]c(C)nc6c5)cc4[nH]3)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.56
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
KMT2A Q03164 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
POLB P06746 2/20 0.56
HSPD1 P10809 1/20 0.56
PTPN2 P17706 1/20 0.56
PTPN1 P18031 1/20 0.56
PTPN5 P54829 1/20 0.56
HSPE1 P61604 1/20 0.56
MAPT P10636 3/20 0.55
NPBWR1 P48145 3/20 0.55
ALDH1A1 P00352 2/20 0.55
NFKB1 P19838 1/20 0.55
MAPK1 P28482 1/20 0.55
HTT P42858 1/20 0.55
NFKB2 Q00653 1/20 0.55
RELA Q04206 1/20 0.55
KDM4E B2RXH2 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11911270 0.95 HSPD1 (0.51) MEN1NPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL13533820 0.92 HSPD1 (0.57) MEN1NPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL34856 0.90 MEN1 (0.68) MEN1NPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL13041694 0.90 MEN1 (0.68) MEN1NPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL13287104 0.90 MEN1 (0.68) MEN1NPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL34880 0.85 MEN1 (0.70) MEN1NPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL12864579 0.85 NPC1 (0.57) MEN1NPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL26357001 0.84 NPC1 (0.67) MEN1NPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL26357465 0.83 CHEK2 (0.60) MEN1NPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL10330717 0.83 CHEK2 (0.51) MEN1NPC1RAB9AKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023160073-A1 HOLLOW FIBER SEPERATION MEMBRANE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 中国石油化工股份有限公司 2023-08-31 WO disclosed