Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636171 | 0.89 | — | — | |
| SCHEMBL2636173 | 0.81 | DGAT1 (0.31) | — | |
| SCHEMBL2635325 | 0.77 | DGAT1 (0.32) | — | |
| SCHEMBL13138748 | 0.75 | HPGDS (0.35) | — | |
| SCHEMBL506792 | 0.74 | ATR (0.36) | USP30 | |
| SCHEMBL667542 | 0.73 | ATR (0.41) | — | |
| SCHEMBL2635099 | 0.72 | ATR (0.39) | — | |
| SCHEMBL506414 | 0.71 | PDPK1 (0.31) | — | |
| SCHEMBL13195655 | 0.71 | USP30 (0.32) | USP30 | |
| SCHEMBL31349701 | 0.71 | USP30 (0.32) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569313-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE | Vertex Pharmaceuticals Incorporated (US) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011143426-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-11-17 | — | — | WO | disclosed |