Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 2/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5121758 | 0.85 | ALDH1A1 (0.68) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL7709727 | 0.85 | ALDH1A1 (0.68) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL7270310 | 0.85 | ALDH1A1 (0.68) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL11981360 | 0.83 | ALDH1A1 (0.52) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL11896998 | 0.83 | ALDH1A1 (0.52) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL5710904 | 0.81 | ALDH1A1 (0.62) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL10977219 | 0.76 | ALDH1A1 (0.55) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL10974938 | 0.76 | ALDH1A1 (0.55) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL10974936 | 0.76 | ALDH1A1 (0.55) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL29987788 | 0.73 | HTR2A (0.59) | ALDH1A1GAAHPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303581-A1 | ORALLY BIOAVAILABLE, BRAIN-PENETRANT COMPOUND WITH SELECTIVITY FOR THE CANNABINOID TYPE 2 RECEPTOR WITH POTENTIAL USE TOWARDS VISCERAL PAIN MANAGEMENT AND NEURODEGENERATIVE DISORDERS | UNIV MISSISSIPPI (US) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303581-A1 | ORALLY BIOAVAILABLE, BRAIN-PENETRANT COMPOUND WITH SELECTIVITY FOR THE CANNABINOID TYPE 2 RECEPTOR WITH POTENTIAL USE TOWARDS VISCERAL PAIN MANAGEMENT AND NEURODEGENERATIVE DISORDERS | CNR2, CNR1, OPRL1 | ALDH1A1 3481/4885GAA 3891/4885HPGD 1245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.