Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.48 |
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709727 | 1.00 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL7270310 | 1.00 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL5710904 | 0.95 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL10977219 | 0.91 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL10974936 | 0.91 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL10974938 | 0.91 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL11896998 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL11981360 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL26359031 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL26359034 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045511-A1 | VISUAL DETECTION OF PBD INDUCED DNA CROSSLINKS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2022-08-24 | — | — | EP | disclosed |
| EP-2650274-B1 | A thionation process and a thionating agent | VIRONOVA THIONATION AB (SE) | 2019-05-01 | — | — | EP | disclosed |
| EP-2650274-B1 | A thionation process and a thionating agent | VIRONOVA THIONATION AB (SE) | 2019-05-01 | — | — | EP | disclosed |
| US-9221855-B2 | Thionation process and a thionating agent | VIRONOVA THIONATION AB (SE) | 2015-12-29 | — | — | US | disclosed |
| US-9221855-B2 | Thionation process and a thionating agent | VIRONOVA THIONATION AB (SE) | 2015-12-29 | — | — | US | disclosed |
| US-9221855-B2 | Thionation process and a thionating agent | VIRONOVA THIONATION AB (SE) | 2015-12-29 | — | — | US | disclosed |
| US-9115158-B2 | Thionating agent | VIRONOVA THIONATION AB (SE) | 2015-08-25 | — | — | US | disclosed |
| US-9115158-B2 | Thionating agent | VIRONOVA THIONATION AB (SE) | 2015-08-25 | — | — | US | disclosed |
| US-9115158-B2 | Thionating agent | VIRONOVA THIONATION AB (SE) | 2015-08-25 | — | — | US | disclosed |
| US-20130303767-A1 | THIONATING AGENT | VIRONOVA THIONATION AB (SE) | 2013-11-14 | — | — | US | disclosed |
| EP-2484655-A1 | A thionation process and a thionating agent | Vironova AB (SE) | 2012-08-08 | — | — | EP | disclosed |
| EP-2484655-A1 | A thionation process and a thionating agent | Vironova AB (SE) | 2012-08-08 | — | — | EP | disclosed |
| US-20080027038-A1 | N-Acylated lipophilic amino acid derivatives | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2008-01-31 | — | — | US | disclosed |
| US-7279573-B2 | Amide derivatives | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2007-10-09 | — | — | US | disclosed |
| EP-1021190-B1 | Amid derivatives as growth hormone release promotors | KAKEN PHARMA CO LTD (JP) | 2006-11-08 | — | — | EP | disclosed |
| EP-0059390-A1 | Imidazodiazepines, intermediate products and process for their preparation, and medicines containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-09-08 | — | — | EP | disclosed |
| US-3985732-A | ANXIOLYTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1976-10-12 | — | — | US | disclosed |
| US-3968230-A | ANTIANXIETY | AMERICAN CYANAMID COMPANY (US) | 1976-07-06 | — | — | US | disclosed |
| US-3947408-A | ANTIANXIETY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1976-03-30 | — | — | US | disclosed |
| US-3732212-A | 1,2,3,10,11,11A-HEXAHYDRO-5H-PYRROLO(2,1-C)(1,4)BENZODIAZEPINE-5,11-DIONES | STERLING DRUG INC | 1973-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303767-A1 | THIONATING AGENT | NT5E, NT5C2, NUDT5 | ALDH1A1 3292/4885KDM4E 4699/4885MAPT 133/4885 |
| US-20080027038-A1 | N-Acylated lipophilic amino acid derivatives | GHRHR, NPPA, SSTR5 | ALDH1A1 2890/4885KDM4E 3946/4885MAPT 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.