Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | ENTPD2 | Q9Y5L3 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686770 | 0.78 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2ALDH1A1MAPK1PKM | |
| SCHEMBL1486740 | 0.77 | KMT2A (0.53) | L3MBTL1SMN1; SMN2ALDH1A1NPY5RRAB9A | |
| SCHEMBL19331999 | 0.77 | NPY5R (0.48) | SMN1; SMN2ALDH1A1NPY5RENTPD2NPC1 | |
| SCHEMBL13003196 | 0.77 | CYP17A1 (0.51) | NPY5RNAMPT | |
| SCHEMBL19682902 | 0.76 | SMN1; SMN2 (0.47) | L3MBTL1SMN1; SMN2ALDH1A1MAPK1PKM | |
| SCHEMBL19331991 | 0.75 | MAPT (0.42) | SMN1; SMN2ALDH1A1NPY5RENTPD2NPC1 | |
| SCHEMBL5277253 | 0.74 | NPY5R (0.43) | ALDH1A1NPY5RENTPD2MAPTENTPD1 | |
| SCHEMBL3024941 | 0.74 | ENPP2 (0.46) | SMN1; SMN2ALDH1A1MAPK1NPY5RENTPD2 | |
| SCHEMBL13924978 | 0.73 | EPHX1 (0.51) | ALDH1A1MAPT | |
| SCHEMBL19066396 | 0.73 | SMN1; SMN2 (0.50) | L3MBTL1SMN1; SMN2ALDH1A1PKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102802672-B | The imaging of myelin basic protein | GENERAL ELECTRIC CO. (US) | 2015-12-16 | — | — | CN | disclosed |
| EP-2437792-B1 | IMAGING OF MYELIN BASIC PROTEIN | GEN ELECTRIC (US) | 2015-10-21 | — | — | EP | disclosed |
| CN-102802672-A | Imaging of myelin basic protein | GEN ELECTRIC | 2012-11-28 | — | — | CN | disclosed |
| EP-2437792-A2 | IMAGING OF MYELIN BASIC PROTEIN | General Electric Company (US) | 2012-04-11 | — | — | EP | disclosed |
| US-20100310456-A1 | IMAGING OF MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
| WO-2010141704-A2 | IMAGING OF MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2010-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310456-A1 | IMAGING OF MYELIN BASIC PROTEIN | MAG, PMP22, MYT1 | L3MBTL1 3209/4885SMN1; SMN2 164/4885ALDH1A1 4822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.