Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.83 |
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 6/20 | 0.40 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL426935 | 1.00 | ALDH1A1 (0.83) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL28552548 | 0.93 | ALDH1A1 (0.71) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL591542 | 0.92 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL6429505 | 0.92 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL842 | 0.91 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL1331942 | 0.91 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL3417188 | 0.91 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL10896997 | 0.91 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL240402 | 0.91 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL725546 | 0.91 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119890413-A | Low-temperature rechargeable lithium ion battery and preparation method thereof | 深圳市量能科技有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-118422494-A | Non-ironing finishing method for cellulose fabric and application of polycarboxylic acid water-soluble ester | 江阴海澜科技有限公司 | 2024-08-02 | — | — | CN | claimed |
| CN-115920917-B | Titanium-containing oxide supported nickel-based catalyst for autothermal reforming of acetic acid to produce hydrogen | 成都理工大学 | 2024-04-05 | — | — | CN | claimed |
| CN-117224730-A | Photo-curing bioactive poly (citrate) -based polyurethane medical adhesive and preparation method thereof | 武汉理工大学 | 2023-12-15 | — | — | CN | claimed |
| CN-113061727-B | Method for selectively leaching metal components in waste lithium cobalt oxide battery by polyethylene glycol-citric acid solvent | 浙江大学衢州研究院 | 2023-05-02 | — | — | CN | claimed |
| CN-115241434-A | Preparation method of lithium-sulfur battery | 哈尔滨理工大学 | 2022-10-25 | — | — | CN | claimed |
| CN-115072793-A | Preparation method of high-crystallinity antioxidant magnetic nanoparticles | 浙江大学台州研究院 | 2022-09-20 | — | — | CN | claimed |
| CN-112795381-B | Perovskite structure fluorescent powder for agricultural illumination and preparation method thereof | 成都理工大学 | 2022-07-08 | — | — | CN | claimed |
| CN-112811882-B | High-stability sensor ceramic material and preparation method thereof | 湖南省美程陶瓷科技有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-108807951-B | Preparation method of lithium battery positive electrode active material | 清远佳致新材料研究院有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-103396684-A | Reinforcing material, and preparation method and application thereof in preparation of thermosensitive film | UNIV SHANDONG | 2013-11-20 | — | — | CN | claimed |
| CN-101973762-B | Preparation method of PMNT ferroelectric film | UNIV SHANGHAI | 2013-03-06 | — | — | CN | claimed |
| CN-101830542-B | Method for electrolyzing orange G by adopting cerium-doped tin antimony oxide coated titanium electrode | UNIV SOUTH CHINA NORMAL | 2011-09-14 | — | — | CN | claimed |
| CN-101973762-A | Preparation method of PMNT ferroelectric film | UNIV SHANGHAI | 2011-02-16 | — | — | CN | claimed |
| WO-2010143783-A2 | IRON-BASED CATALYST FOR FISCHER-TROPSCH SYNTHESIS AND PREPARATION METHOD THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-12-16 | — | — | WO | claimed |
| CN-101830542-A | Method for electrolyzing orange G by adopting cerium-doped tin antimony oxide coated titanium electrode | UNIV SOUTH CHINA NORMAL | 2010-09-15 | — | — | CN | claimed |
| CN-101724908-A | Controllable and mass production method of perovskite type manganese and oxygen compound polycrystal nano-rod function material | USTC UNIV SCIENCE TECH CN | 2010-06-09 | — | — | CN | claimed |
| CN-101532976-A | SmFeO3-based conductance acetone gas sensitive material, preparation method and application thereof | UNIV TIANJIN | 2009-09-16 | — | — | CN | claimed |
| CN-100337946-C | Method for treating ephedrine wastewater by combined use of flocculation and electrochemical oxidation | UNIV YANGZHOU (CN) | 2007-09-19 | — | — | CN | claimed |
| CN-1803674-A | Method for treating ephedrine wastewater by combined use of flocculation and electrochemical oxidation | UNIV YANGZHOU (CN) | 2006-07-19 | — | — | CN | claimed |