Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.72 |
| ▸ | TNKS | O95271 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26370891 | 0.88 | HRH3 (0.72) | HRH3TNKSSMN1; SMN2JAK2CHEK1 | |
| SCHEMBL16883444 | 0.87 | HRH3 (0.59) | HRH3TNKSSMN1; SMN2NPC1RAB9A | |
| SCHEMBL24061141 | 0.83 | HRH3 (0.82) | HRH3SMN1; SMN2JAK2NPC1RAB9A | |
| SCHEMBL19390864 | 0.83 | HRH3 (0.60) | HRH3TNKSSMN1; SMN2JAK2CHEK1 | |
| SCHEMBL13161945 | 0.82 | HRH3 (0.62) | HRH3TNKSSMN1; SMN2NPC1RAB9A | |
| SCHEMBL13376445 | 0.82 | HRH3 (0.68) | HRH3TNKSSMN1; SMN2JAK2CHEK1 | |
| SCHEMBL30616059 | 0.81 | HRH3 (0.57) | HRH3TNKSJAK2CHEK1NPC1 | |
| SCHEMBL4469770 | 0.81 | HRH3 (0.61) | HRH3TNKSSMN1; SMN2JAK2CHEK1 | |
| SCHEMBL4465612 | 0.80 | HRH3 (0.59) | HRH3TNKSSMN1; SMN2NPC1RAB9A | |
| SCHEMBL19869673 | 0.79 | HRH3 (0.59) | HRH3TNKSCHEK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3572400-B1 | EZH2 INHIBITOR AND USE THEREOF | TARAPEUTICS SCIENCE INC (CN) | 2023-10-04 | — | — | EP | disclosed |