SCHEMBL4465612

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4469770	0.87	HRH3 (0.61)	HRH3PDE4BCYP2A13TNKSSMN1; SMN2
	SCHEMBL4473916	0.86	HRH3 (0.63)	HRH3USP2TSHRPDE4BCYP2A13
	SCHEMBL13161945	0.81	HRH3 (0.62)	HRH3USP2TSHRCYP2A13KMT2A
	SCHEMBL24495610	0.80	ALDH1A1 (0.60)	HRH3SMN1; SMN2KDM4EALDH1A1HTT
	SCHEMBL26371010	0.80	HRH3 (0.72)	HRH3USP2TSHRCYP2A13TNKS
	SCHEMBL4480082	0.78	KDM4E (0.56)	HRH3CYP2A13SMN1; SMN2KDM4EALDH1A1
	SCHEMBL4480084	0.78	KDM4E (0.56)	HRH3CYP2A13SMN1; SMN2KDM4EALDH1A1
	4-(4-Chlorobenzyl)Morpholine SCHEMBL4103722	0.78	HRH3 (0.74)	HRH3USP2TSHRCYP2A13KMT2A
	SCHEMBL14907097	0.78	CYP2A13 (0.67)	USP2TSHRCYP2A13KMT2ANPSR1
	SCHEMBL4476534	0.78	CNR2 (0.71)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.